SLC22A11

Gene Name		solute carrier family 22 (organic anion/urate transporter), member 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Inorganic Anion Exchanger Activity Protein Binding Organic Anion Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Organic Anion Transport Urate Metabolic Process Transmembrane Transport
Pathways		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Organic anion transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport
Drugs		Probenecid
Diseases
GWAS		Obesity-related traits ( 23251661) Urate levels ( 20884846 23263486) Uric acid levels ( 19503597)
Protein-protein Interactions		3 interactors: CAV3 PDZK1 SLC9A3R1
Entrez ID		55867
HPRD ID		06161
Ensembl ID		ENSG00000168065
Uniprot IDs		Q9NSA0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Ion Transmembrane Transport Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Regulation Of Ion Transport Regulation Of Sodium Ion Transport Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Ion Transport Regulation Of Protein Kinase B Signaling Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Protein Localization To Plasma Membrane Regulation Of Signal Transduction By Receptor Internalization Negative Regulation Of Sarcomere Organization Renal Phosphate Ion Absorption Regulation Of Nerve Growth Factor Receptor Activity Negative Regulation Of MAPK Cascade Cellular Protein Localization Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Plasma Membrane Organization Establishment Of Protein Localization To Membrane Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development T-tubule Organization Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Carboxylic Acid Transport Organic Acid Transport Protein Localization Renal Sodium Ion Transport Regulation Of Membrane Depolarization During Action Potential Cellular Phosphate Ion Homeostasis Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cardiac Muscle Cell Differentiation Protein Localization To Membrane Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Transport Negative Regulation Of Phosphorylation Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Caveolin-mediated Endocytosis Caveola Assembly Negative Regulation Of Intracellular Signal Transduction Endomembrane System Organization Negative Regulation Of Protein Localization To Cell Surface
Tagcloud ?		aetiology ancestry college direction equivocal european europeans gckr genotyped gout hlf inconsistency inhbc loci maaori maf meeting obvious opposing pacific pdzk1 polynesian prkag2 replicated rheumatology sizes slc16a9 urate zealand