N4BP2

Description		NEDD4 binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Endonuclease Activity DNA Endonuclease Activity Protein Binding ATP Binding Hydrolase Activity Ubiquitin Binding ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity
	Biological Process	DNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Platelet thrombus formation ( 22550155)
Interacting Genes		5 interacting genes: BCL3 CREBBP EP300 NEDD4 TOLLIP
Entrez ID		55728
HPRD ID		11382
Ensembl ID		ENSG00000078177
Uniprot IDs		B2ZZ87 Q86UW6
PDB IDs		2D9I 2VKC 3BHB 3FAU
Enriched GO Terms of Interacting Partners?		Response To UV Histone H3K27 Acetyltransferase Activity Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Canonical NF-kappaB Signal Transduction Response To Light Stimulus Cellular Response To UV Response To Radiation Cellular Response To Light Stimulus Transcription Coregulator Activity N-terminal Protein Amino Acid Acetylation Leukocyte Activation Peptidyl-lysine Acetylation Regulation Of Cellular Response To Heat Protein Localization To Organelle Cell Activation Cellular Response To Radiation DNA-binding Transcription Factor Binding Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Immune System Process Protein-containing Complex Histone Acetyltransferase Complex DNA Damage Response Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Acetylation Transcription Coactivator Activity Tau Protein Binding Regulation Of Cellular Response To Growth Factor Stimulus Transcription Coactivator Binding Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein Destabilization Positive Regulation Of Nucleocytoplasmic Transport Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Damaged DNA Binding P53 Binding Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response Lymphocyte Activation Positive Regulation Of Macromolecule Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Stress Negative Regulation Of RNA Metabolic Process
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