ITLN1

Description		intelectin 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Brush Border Membrane Receptor Complex Membrane Raft Extracellular Exosome Side Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding Oligosaccharide Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Response To Nematode Positive Regulation Of D-glucose Import Protein Homotrimerization
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 21102463 28067908) Inflammatory bowel disease ( 23128233 28067908)
Interacting Genes		1 interacting genes: LTF
Entrez ID		55600
HPRD ID		17165
Ensembl ID		ENSG00000179914
Uniprot IDs		Q8WWA0
PDB IDs		4WMQ 4WMY 6USC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Positive Regulation Of Bone Mineralization Involved In Bone Maturation Phagocytic Vesicle Lumen Membrane Destabilizing Activity Negative Regulation Of Osteoclast Development Negative Regulation Of ATP-dependent Activity Cytolysis By Host Of Symbiont Cells Negative Regulation Of Membrane Potential Specific Granule Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Antifungal Humoral Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Osteoclast Development Positive Regulation Of Chondrocyte Proliferation Positive Regulation Of Osteoblast Proliferation Host-mediated Suppression Of Viral Proces Innate Immune Response In Mucosa Cysteine-type Endopeptidase Inhibitor Activity Lipopolysaccharide Binding Bone Morphogenesis Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Osteoblast Proliferation Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of ATP-dependent Activity Biological Process Involved In Interaction With Symbiont Mucosal Immune Response Negative Regulation Of Osteoclast Differentiation Killing By Host Of Symbiont Cells Organ Or Tissue Specific Immune Response Positive Regulation Of Bone Mineralization Iron Ion Transport Tertiary Granule Lumen Defense Response To Fungus Positive Regulation Of Ossification Negative Regulation Of Viral Genome Replication Positive Regulation Of Biomineral Tissue Development Negative Regulation Of Myeloid Leukocyte Differentiation Specific Granule Lumen Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Fungus Antibacterial Humoral Response Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Osteoclast Differentiation Protein Serine/threonine Kinase Activator Activity Regulation Of Viral Genome Replication Positive Regulation Of Osteoblast Differentiation Host-mediated Perturbation Of Viral Process Regulation Of Bone Mineralization
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