NAT10

Description		N-acetyltransferase 10
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Membrane Midbody Small-subunit Processome
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Protein Binding ATP Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups TRNA Cytidine N4-acetyltransferase Activity DNA Polymerase Binding MRNA N-acetyltransferase Activity 18S RRNA Cytidine N-acetyltransferase Activity
	Biological Process	RRNA Modification TRNA Wobble Cytosine Modification RRNA Processing Regulation Of Translation Protein Acetylation TRNA Processing RNA Modification Regulation Of Centrosome Duplication RRNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Ribosome Biogenesis Ribosomal Small Subunit Biogenesis Positive Regulation Of Translation TRNA Acetylation RRNA Acetylation Involved In Maturation Of SSU-rRNA
Pathways		rRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: CD2BP2 CENATAC MDM2 PARP1 SREK1 SUMO2 TP53 UBC UBE2D2 UBE2I USP7
Entrez ID		55226
HPRD ID		10964
Ensembl ID		ENSG00000135372
Uniprot IDs		Q9H0A0
PDB IDs		6VLA 7MQ8 7MQ9
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification SUMO Transferase Activity PML Body Ubiquitin Protein Ligase Binding Macromolecule Metabolic Process Cellular Response To Actinomycin D Protein Modification By Small Protein Conjugation Nuclear Body Response To Actinomycin D Nucleoplasm Cellular Response To UV-C Response To Gamma Radiation Protein Sumoylation Mitochondrial DNA Repair P53 Binding Protein Modification Process Positive Regulation Of Programmed Necrotic Cell Death Cellular Response To Antibiotic Cellular Response To UV Cellular Response To Light Stimulus Regulation Of Telomere Maintenance Proteolysis Response To UV-C Protein Tag Activity Regulation Of Circadian Rhythm Negative Regulation Of Small Molecule Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Mitochondrial DNA Metabolic Process Protein-containing Complex Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Enzyme Binding Response To Ionizing Radiation Negative Regulation Of Proteolysis Response To UV Disordered Domain Specific Binding Cellular Response To Gamma Radiation Presynaptic Cytosol Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Cellular Response To Radiation Postsynaptic Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of Programmed Necrotic Cell Death Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Telomere Maintenance Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
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