AVPR1A

Gene Name		arginine vasopressin receptor 1A
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Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Vasopressin Receptor Activity Protein Kinase C Binding Protein Binding Peptide Hormone Binding V1A Vasopressin Receptor Binding Peptide Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin Maternal Aggressive Behavior Positive Regulation Of Systemic Arterial Blood Pressure Generation Of Precursor Metabolites And Energy G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Female Receptivity Grooming Behavior Blood Circulation Positive Regulation Of Cell Proliferation Positive Regulation Of Heart Rate Positive Regulation Of Glutamate Secretion Myotube Differentiation Calcium-mediated Signaling Telencephalon Development Positive Regulation Of Cell Growth Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Cellular PH Reduction Cellular Response To Hormone Stimulus Social Behavior Positive Regulation Of Renal Sodium Excretion Cellular Response To Water Deprivation Maternal Behavior Sperm Ejaculation Penile Erection Positive Regulation Of Vasoconstriction Response To Corticosterone Negative Regulation Of Transmission Of Nerve Impulse Response To Peptide
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Vasopressin-like receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Desmopressin Vasopressin Felypressin Conivaptan Terlipressin Tolvaptan
Diseases
GWAS
Protein-protein Interactions		3 interactors: AVP GRK5 PRKCA
Entrez ID		552
HPRD ID		02894
Ensembl ID
Uniprot IDs		P37288
PDB IDs		1YTV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cell Death Death Negative Regulation Of Signal Transduction Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Signaling Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Phosphorylation Histone H3-T6 Phosphorylation Protein Autophosphorylation Regulation Of Apoptotic Process Regulation Of Cell Death Cellular Calcium Ion Homeostasis Maternal Aggressive Behavior Positive Regulation Of Cellular PH Reduction Negative Regulation Of Transmission Of Nerve Impulse Penile Erection Calcium Ion Homeostasis Phosphorylation Positive Regulation Of Glutamate Secretion Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Prostaglandin Biosynthetic Process Regulation Of Cellular Amino Acid Metabolic Process Cellular Metal Ion Homeostasis Generation Of Precursor Metabolites And Energy Cellular Cation Homeostasis Cellular Ion Homeostasis Negative Regulation Of Female Receptivity Desmosome Assembly Hyperosmotic Salinity Response Tachykinin Receptor Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Metal Ion Homeostasis Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Glucose Import Positive Regulation Of Amino Acid Transport Positive Regulation Of Macrophage Differentiation Aggressive Behavior Regulation Of Transmission Of Nerve Impulse Sodium-independent Organic Anion Transport
Tagcloud ?		aldosterone bdkrb2 caucasians dbsnp functionality genotyped imply infarction infarctions leiden microrna mineralocorticoid myocardial nr3c2 raas renin rs11174811 rs13306046 rs2069591 rs5225 rs5534 smile snp snps targetscan tbxa2r thromboxane twofold vasopressin