SEC61A2

Description		SEC61 translocon subunit alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Signal Sequence Binding Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Transport Post-translational Protein Targeting To Membrane, Translocation
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: APOB TOMM6
Entrez ID		55176
HPRD ID		15317
Ensembl ID		ENSG00000065665
Uniprot IDs		B3KQ68 Q8TC24 Q9H9S3
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipoprotein Transport Positive Regulation Of Macrophage Derived Foam Cell Differentiation Protein-lipid Complex Assembly Low-density Lipoprotein Particle Remodeling Lipoprotein Metabolic Process Mature Chylomicron Endosome Lumen Triglyceride Mobilization Triglyceride Catabolic Process Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Receptor Binding Acylglycerol Catabolic Process Chylomicron Positive Regulation Of Cholesterol Storage Protein Transport Endocytic Vesicle Lumen Very-low-density Lipoprotein Particle Assembly Lipoprotein Biosynthetic Process Lipid Transporter Activity Cholesterol Efflux Cholesterol Transfer Activity Low-density Lipoprotein Particle Regulation Of Cholesterol Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Smooth Endoplasmic Reticulum Lipoprotein Catabolic Process Chylomicron Remnant Positive Regulation Of Lipid Storage Low-density Lipoprotein Particle Clearance Intermediate-density Lipoprotein Particle Plasma Lipoprotein Particle Clearance Plasma Lipoprotein Particle Assembly Lipase Binding Endoplasmic Reticulum Exit Site Mitochondrial Outer Membrane Translocase Complex TOM Complex Protein Insertion Into Mitochondrial Outer Membrane Establishment Of Protein Localization To Mitochondrial Membrane Protein Insertion Into Mitochondrial Membrane Plasma Lipoprotein Particle Remodeling Cellular Response To Lipoprotein Particle Stimulus Protein-containing Complex Remodeling Regulation Of Lipid Storage Establishment Of Protein Localization Regulation Of Cholesterol Metabolic Process Cellular Response To Amyloid-beta Triglyceride Metabolic Process Response To Amyloid-beta Artery Morphogenesis Cholesterol Transport
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