THG1L

Gene Name		tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion
	Molecular Function	TRNA Binding Magnesium Ion Binding ATP Binding GTP Binding TRNA Guanylyltransferase Activity Identical Protein Binding
	Biological Process	TRNA Modification TRNA Processing Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ELMOD1 SDCBP TERF1 UBC
Entrez ID		54974
HPRD ID		13726
Ensembl ID
Uniprot IDs		B4E366 Q9NWX6
PDB IDs		3OTB 3OTC 3OTD 3OTE
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Telomere Maintenance Via Telomere Shortening Positive Regulation Of Extracellular Vesicular Exosome Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Transferase Activity Positive Regulation Of Cellular Component Biogenesis Replicative Cell Aging Regulation Of Protein Catabolic Process Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Mitotic Cell Cycle Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Regulation Of Telomere Maintenance Via Telomerase Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of MAPK Cascade Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Positive Regulation Of Apoptotic Process RNA-dependent DNA Replication Positive Regulation Of Programmed Cell Death Notch Receptor Processing Regulation Of Catalytic Activity Negative Regulation Of DNA Biosynthetic Process Virion Assembly Positive Regulation Of Cell Death Regulation Of MAPK Cascade Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Organelle Assembly
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