GEMIN8

Description		gem nuclear organelle associated protein 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP DYRK1A RN7SL1 RNU1-1 RNU2-1 TSC1
Entrez ID		54960
HPRD ID		06533
Ensembl ID		ENSG00000046647
Uniprot IDs		Q9NWZ8
PDB IDs		7BBL
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Actin Filament Histone H3T45 Kinase Activity Pre-mRNA Branch Point Binding MRNA Branch Site Recognition Memory T Cell Differentiation Associative Learning Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization TSC1-TSC2 Complex Adult Behavior Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cell Activation Involved In Immune Response Cellular Response To Norepinephrine Stimulus Learning Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Negative Regulation Of Heterochromatin Formation ATPase Inhibitor Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Locomotory Behavior Regulation Of Neurofibrillary Tangle Assembly Splicing Factor Binding
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