KANSL2

Description		KAT8 regulatory NSL complex subunit 2
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Mitochondrion Cytosol Plasma Membrane Actin Cytoskeleton NSL Complex
	Molecular Function	Protein Binding
	Biological Process	Chromatin Organization Positive Regulation Of DNA-templated Transcription
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Letter-number span reordering ( 31596458)
Interacting Genes		4 interacting genes: APP IKBKG TSC1 TTC3
Entrez ID		54934
HPRD ID		07907
Ensembl ID		ENSG00000139620
Uniprot IDs		Q9H9L4
PDB IDs		4CY2
Enriched GO Terms of Interacting Partners?		Protein-folding Chaperone Binding Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Adult Locomotory Behavior Associative Learning Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Memory T Cell Differentiation Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cell Activation Involved In Immune Response Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Growth Cone Filopodium Protein-containing Complex Learning Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Locomotory Behavior Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization TSC1-TSC2 Complex Linear Polyubiquitin Binding Regulation Of Macroautophagy Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Intracellular Signal Transduction Growth Factor Receptor Binding Main Axon ATPase Inhibitor Activity Immune Response Regulation Of Cell Junction Assembly Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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