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ALKBH5
Gene Name
AlkB family member 5, RNA demethylase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nuclear Speck
Molecular Function
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors
Oxidative RNA Demethylase Activity
Poly(A) RNA Binding
Metal Ion Binding
Biological Process
Response To Hypoxia
MRNA Processing
MRNA Export From Nucleus
Spermatogenesis
Cell Differentiation
Oxidative Single-stranded RNA Demethylation
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-protein Interactions
1 interactors:
CSNK2A1
Entrez ID
54890
HPRD ID
08621
Ensembl ID
ENSG00000091542
Uniprot IDs
Q6P6C2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chaperone-mediated Protein Folding
Negative Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cell Division
Regulation Of Chromosome Segregation
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Chromosome Organization
Negative Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Growth
Regulation Of Mitotic Nuclear Division
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Wnt Signaling Pathway
Mitotic Cell Cycle Checkpoint
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Chromosome Organization
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Growth
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Regulation Of Cell Division
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Wnt Signaling Pathway
Protein Folding
Regulation Of Wnt Signaling Pathway
Rhythmic Process
Regulation Of Cell Growth
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Regulation Of Endopeptidase Activity
Regulation Of Protein Catabolic Process
Axon Guidance
Negative Regulation Of Hydrolase Activity
Regulation Of Protein Processing
Regulation Of Mitotic Cell Cycle
Regulation Of Peptidase Activity
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