SHLD2

Description		shieldin complex subunit 2
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Actin Cytoskeleton Site Of Double-strand Break
	Molecular Function	Protein Binding
	Biological Process	Somatic Diversification Of Immunoglobulins Involved In Immune Response DNA Repair DNA Damage Response Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance In Response To DNA Damage Positive Regulation Of Isotype Switching Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Drugs
Diseases
GWAS		Gout ( 32238385) Gout (combined type) ( 32238385) Renal underexcretion gout ( 32238385)
Interacting Genes		2 interacting genes: SHLD1 TMEM132D
Entrez ID		54537
HPRD ID		09944
Ensembl ID		ENSG00000122376
Uniprot IDs		Q86V20
PDB IDs		6KTO 6WWA 7L9P
Enriched GO Terms of Interacting Partners?		Regulation Of Isotype Switching Negative Regulation Of DNA Repair Positive Regulation Of Immunoglobulin Mediated Immune Response Telomere Maintenance In Response To DNA Damage Positive Regulation Of Immunoglobulin Production Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of DNA Recombination Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Somatic Diversification Of Immunoglobulins Negative Regulation Of Double-strand Break Repair
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