HEATR5B

Description		HEAT repeat containing 5B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Clathrin-coated Vesicle Endocytic Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Endocytosis Intracellular Protein Localization Protein Transport Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 28552196) QRS duration ( 30012220) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30578418) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: AP1G1 KDM8
Entrez ID		54497
HPRD ID		11145
Ensembl ID		ENSG00000008869
Uniprot IDs		Q9P2D3
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Budding From Endosome Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation Peptidyl-arginine 3-dioxygenase Activity Golgi To Lysosome Transport Endosome To Melanosome Transport AP-1 Adaptor Complex Histone H3K36 Demethylase Activity Clathrin Adaptor Activity Intracellular Vesicle Golgi To Vacuole Transport GTP-dependent Protein Binding Melanosome Assembly Platelet Dense Granule Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Clathrin-coated Vesicle Membrane Vesicle Budding From Membrane Synaptic Vesicle Endocytosis Melanosome Organization Membrane Coat Pigment Granule Organization Aminopeptidase Activity Fibroblast Proliferation Presynaptic Endocytosis Kinesin Binding Positive Regulation Of Regulated Secretory Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity G2/M Transition Of Mitotic Cell Cycle Regulation Of Natural Killer Cell Mediated Immunity Cell Cycle G2/M Phase Transition Protein Destabilization Collagen Binding Secretory Granule Organization Clathrin-coated Pit Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Circadian Regulation Of Gene Expression P53 Binding Clathrin-coated Vesicle Dioxygenase Activity Positive Regulation Of Exocytosis Endopeptidase Activity Vesicle-mediated Transport In Synapse Regulation Of Leukocyte Mediated Cytotoxicity Post-Golgi Vesicle-mediated Transport
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