OTULINL

Description		OTU deubiquitinase with linear linkage specificity like
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Ubiquitin-like Protein Peptidase Activity Ubiquitin Binding
	Biological Process	Protein Deubiquitination
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059 34103634)
Interacting Genes		10 interacting genes: AQP6 GOLT1A HSD17B11 JAGN1 RETREG3 SLC30A8 TMEM14B TMEM31 TMEM86B TMX2
Entrez ID		54491
HPRD ID		07733
Ensembl ID		ENSG00000145569
Uniprot IDs		Q9NUU6
PDB IDs		6DRM
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Insulin Metabolic Process PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Insulin Secretion Peptide Hormone Secretion Endoplasmic Reticulum Organization Peptide Secretion D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Hormone Secretion Carbon Dioxide Transmembrane Transporter Activity Membrane Carbon Dioxide Transmembrane Transport Endoplasmic Reticulum Membrane Steroid Dehydrogenase Activity Androgen Catabolic Process Regulation Of Hormone Levels Protein Localization To Extracellular Region Granulocyte Colony-stimulating Factor Signaling Pathway Response To Monosaccharide Hormone Transport Establishment Of Protein Localization To Extracellular Region Response To Glucose Protein Secretion Amide Transport Peptide Transport Endoplasmic Reticulum-autophagosome Adaptor Activity Zinc:proton Antiporter Activity Monoatomic Anion Channel Activity Ammonium Channel Activity Renal Water Transport Disulfide Oxidoreductase Activity Mitochondrial Membrane Hormone Metabolic Process Estrogen Biosynthetic Process Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Insulin Secretion Response To Carbohydrate Signal Release Neutrophil Differentiation Substrate Localization To Autophagosome Zinc Ion Import Across Plasma Membrane Insulin Processing Ammonium Transmembrane Transport Regulation Of Peptide Hormone Secretion Zinc Ion Import Into Organelle Golgi Cis Cisterna
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