PON2

Gene Name		paraoxonase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Mitochondrion Lysosome Plasma Membrane
	Molecular Function	Arylesterase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Response To Oxidative Stress Aromatic Compound Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: GRB2 HTR2A
Entrez ID		5445
HPRD ID		03903
Ensembl ID		ENSG00000105854
Uniprot IDs		J3QT77 Q15165
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-mediated Signaling Phospholipase C-activating Serotonin Receptor Signaling Pathway Aging Positive Regulation Of Phosphatidylinositol Biosynthetic Process Positive Regulation Of Phospholipid Biosynthetic Process Artery Smooth Muscle Contraction Tonic Smooth Muscle Contraction Regulation Of MAPK Cascade Urinary Bladder Smooth Muscle Contraction Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Glycolytic Process Serotonin Receptor Signaling Pathway Vascular Smooth Muscle Contraction Behavioral Response To Cocaine Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Organonitrogen Compound Sleep Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cell-cell Signaling Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Protein Localization To Cytoskeleton Regulation Of Dopamine Secretion Labyrinthine Layer Morphogenesis Negative Regulation Of Potassium Ion Transport Phosphatidylinositol 3-kinase Signaling Temperature Homeostasis Response To Abiotic Stimulus Regulation Of Glycolytic Process Embryonic Placenta Morphogenesis Detection Of Temperature Stimulus Negative Regulation Of Signaling Sensory Perception Of Temperature Stimulus Positive Regulation Of Vasoconstriction Vasoconstriction Positive Regulation Of Signal Transduction Release Of Sequestered Calcium Ion Into Cytosol Detection Of Mechanical Stimulus Involved In Sensory Perception Regulation Of Phosphorylation Regulation Of Sequestering Of Calcium Ion Receptor Internalization Calcium Ion Transport Into Cytosol Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cytosolic Calcium Ion Transport Detection Of Mechanical Stimulus Regulation Of Phosphorus Metabolic Process Negative Regulation Of ERBB Signaling Pathway Response To Cocaine Activation Of Phospholipase C Activity Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Phospholipase C Activity
Tagcloud ?		acyltransferase allozymes apoj apolipoproteins atherosclerotic catabolite cholesteryl conflicting equally gln hydrolase hydrolyze hydroperoxides incompletely incorporating insecticide lecithin leu lipoprotein lipoproteins originally paraoxon paraoxonase parathion phospholipids physiologic pon1 pon3