TREM1

Gene Name		triggering receptor expressed on myeloid cells 1
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Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity Scaffold Protein Binding
	Biological Process	Cytokine Secretion Involved In Immune Response Humoral Immune Response Blood Coagulation Neutrophil Chemotaxis Intracellular Signal Transduction Innate Immune Response Chemokine Metabolic Process Leukocyte Migration Neutrophil Mediated Killing Of Gram-negative Bacterium Neutrophil Extravasation
Pathways		DAP12 interactions Cell surface interactions at the vascular wall Innate Immune System
Drugs		D-tartaric acid
Diseases
GWAS
Protein-protein Interactions		1 interactors: TYROBP
Entrez ID		54210
HPRD ID		05472
Ensembl ID		ENSG00000124731
Uniprot IDs		K7EJW1 Q38L15 Q9NP99
PDB IDs		1Q8M 1SMO
Enriched GO Terms of Interacting Partners?		Regulation Of Osteoclast Development Neutrophil Activation Involved In Immune Response Macrophage Activation Involved In Immune Response Neutrophil Activation Macrophage Activation Cellular Defense Response Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Integrin-mediated Signaling Pathway Leukocyte Activation Involved In Immune Response Regulation Of Myeloid Cell Differentiation
Tagcloud ?		1x10 3x10 6x10 7x10 9x10 aging cohorts copyright cytometric decline endophenotypes gwas intronic neuritic neurofibrillary neuropathological plaques pursue reserved rights rs6910730g rs7759295c tangle tangles trem2 treml2 triggering variants