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TLR9
Gene Name
toll-like receptor 9
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Extracellular Region
Cytoplasm
Lysosome
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Endosome Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Early Phagosome
Endolysosome Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Interleukin-1 Receptor Binding
SiRNA Binding
Biological Process
Toll-like Receptor Signaling Pathway
Response To Molecule Of Bacterial Origin
MyD88-dependent Toll-like Receptor Signaling Pathway
Inflammatory Response
I-kappaB Phosphorylation
Insulin Receptor Signaling Pathway
Maintenance Of Gastrointestinal Epithelium
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Interleukin-8 Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Interferon-beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-18 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
Positive Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of NF-kappaB Import Into Nucleus
Defense Response To Bacterium
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Interferon-gamma Biosynthetic Process
Innate Immune Response
Positive Regulation Of Interferon-alpha Biosynthetic Process
Positive Regulation Of Interferon-beta Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of JNK Cascade
Regulation Of Cytokine Secretion
Positive Regulation Of Inflammatory Response
Defense Response To Gram-negative Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Pathways
Insulin receptor signalling cascade
IRS-mediated signalling
Toll Like Receptor 7/8 (TLR7/8) Cascade
IRS-related events
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Trafficking and processing of endosomal TLR
Toll-Like Receptors Cascades
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
MyD88 dependent cascade initiated on endosome
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
Toll Like Receptor 9 (TLR9) Cascade
PI3K Cascade
PI3K Cascade
Innate Immune System
Signaling by Insulin receptor
Drugs
Chloroquine
Hydroxychloroquine
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-protein Interactions
6 interactors:
BTK
HRAS
MAPK8IP3
RNF216
SIGIRR
TLR1
Entrez ID
54106
HPRD ID
05685
Ensembl ID
ENSG00000239732
Uniprot IDs
Q9NR96
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Cytokine Production
Inflammatory Response
Lung Morphogenesis
Regulation Of Immune System Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Defense Response
Immune Response-regulating Signaling Pathway
Toll-like Receptor 1 Signaling Pathway
Regulation Of B Cell Cytokine Production
Regulation Of Cytokine Biosynthetic Process
Toll-like Receptor Signaling Pathway
Response To Stress
Positive Regulation Of JNK Cascade
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Response To External Stimulus
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Cellular Response To Molecule Of Fungal Origin
Detection Of Triacyl Bacterial Lipopeptide
Cellular Response To Triacyl Bacterial Lipopeptide
Activation Of Innate Immune Response
Regulation Of JNK Cascade
Innate Immune Response
Positive Regulation Of Innate Immune Response
Regulation Of Immune Response
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Metabolic Process
Response To Molecule Of Fungal Origin
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Rac Protein Signal Transduction
Negative Regulation Of Chemokine Biosynthetic Process
Apoptotic Process
Fc-epsilon Receptor Signaling Pathway
MAPK Cascade
Programmed Cell Death
Positive Regulation Of MiRNA Metabolic Process
Regulation Of Innate Immune Response
Cell Death
Death
Positive Regulation Of Ruffle Assembly
Detection Of Bacterial Lipoprotein
Lung Development
Respiratory Tube Development
Fc Receptor Signaling Pathway
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Signal Transduction By Phosphorylation
Respiratory System Development
Regulation Of MAP Kinase Activity
Tagcloud
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