CLDN22

Description		claudin 22
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways		Tight junction interactions
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: CLEC4C CXCR2 LHFPL5 OPRM1 SPG21 TMBIM6 TREX1
Entrez ID		53842
HPRD ID		13068
Ensembl ID		ENSG00000177300
Uniprot IDs		Q8N7P3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cytosolic Calcium Ion Concentration Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Regulation Of Immunoglobulin Production Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Interleukin-8 Receptor Activity Secretory Granule Membrane Interleukin-8-mediated Signaling Pathway Endoribonuclease Inhibitor Activity Cellular Response To Type I Interferon DNA Exonuclease Activity Retrotransposition Transposition Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Interleukin-8 Binding Myeloid Leukocyte Activation Cellular Response To Morphine DNA Synthesis Involved In UV-damage Excision Repair Mast Cell Granule Membrane Regulation Of NMDA Receptor Activity System Process T Cell Antigen Processing And Presentation Negative Regulation Of Calcium Ion Transport Into Cytosol G Protein-coupled Opioid Receptor Activity Calcium Ion Transmembrane Transport Regulation Of Production Of Molecular Mediator Of Immune Response Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response MutSalpha Complex Binding Double-stranded DNA 3'-5' DNA Exonuclease Activity MutLalpha Complex Binding C-X-C Chemokine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Immune System Process Behavioral Response To Ethanol Calcium Ion Transport G Protein-coupled Opioid Receptor Signaling Pathway Nervous System Process IRE1-mediated Unfolded Protein Response 3'-5'-DNA Exonuclease Activity CD4 Receptor Binding Stereocilium Bundle Monoatomic Ion Transport Negative Regulation Of Immunoglobulin Production Cellular Response To Hydroxyurea
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