PLOD1

Gene Name		procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Protein Homodimerization Activity
	Biological Process	Response To Hypoxia Cellular Protein Modification Process Epidermis Development Extracellular Matrix Organization Hydroxylysine Biosynthetic Process Oxidation-reduction Process
Pathways		Collagen formation Collagen biosynthesis and modifying enzymes
Drugs		Vitamin C Succinic acid
Diseases
GWAS
Protein-protein Interactions		1 interactors: USP4
Entrez ID		5351
HPRD ID		01086
Ensembl ID		ENSG00000083444
Uniprot IDs		B4DR87 Q02809
PDB IDs
Enriched GO Terms of Interacting Partners?		Spliceosomal Tri-snRNP Complex Assembly Protein Localization To Cell Surface Spliceosomal SnRNP Assembly Negative Regulation Of Protein Ubiquitination Protein Deubiquitination Protein Modification By Small Protein Removal Regulation Of Protein Stability Ribonucleoprotein Complex Assembly Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process
Tagcloud ?		activates biogenesis biopsies breast collagen constituent ecm encoding fibrillar hif hydroxylases hypoxia hypoxic inducible intratumoral lungs lymph lysyl majority matrix metastasis metastatic mortality nodes plod2 procollagen stiffness therapies treat