TM6SF2

Name	transmembrane 6 superfamily member 2
Structure	No pdb structure
Interactors	10 interactors: ARL13B BCL2L13 FAM209A HIBADH KCNJ6 MUC1 PVR SCN3B SSMEM1 TMEM237
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Regulation Of Lipid Metabolic Process Lipid Homeostasis
GWAS	Alanine aminotransferase levels ( 34315874 33547301 33339817 ) Alcohol-related hepatocellular carcinoma ( 34902334 ) Aspartate aminotransferase levels ( 34315874 33547301 ) Bipolar disorder ( 31043756 ) Bipolar I disorder ( 31043756 ) Bipolar II disorder ( 31043756 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Brain morphology (MOSTest) ( 32665545 ) Cirrhosis (alcohol related) ( 26482880 ) Cirrhosis (multi-trait analysis) ( 33310085 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) Hemoglobin levels ( 32327693 ) Liver enzyme levels (alanine transaminase) ( 33972514 ) Liver fat content (MRI proton density fat fraction measure) ( 32247823 ) Liver fibrosis and steatohepatitis severity (MRI cT1 measure) ( 32247823 ) Low density lipoprotein cholesterol levels ( 32154731 ) Medication use (HMG CoA reductase inhibitors) ( 31015401 ) Nonalcoholic fatty liver disease ( 34841290 24531328 29385134 ) Nonalcoholic steatohepatitis ( 32298765 ) Percent liver fat ( 34128465 ) Schizophrenia ( 23974872 25056061 29483656 ) Serum alkaline phosphatase levels ( 33547301 ) Serum metabolite levels ( 33031748 ) Triglyceride levels ( 33339817 29403010 32203549 32154731 ) Type 2 diabetes ( 29632382 30297969 ) Type 2 diabetes (adjusted for BMI) ( 29632382 ) Vitamin levels ( 23696881 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	53345
HPRD ID	12109
Ensembl ID	ENSG00000213996
Uniprot IDs	Q9BZW4
PDB IDs	Not available