PLAG1

Gene Name		pleiomorphic adenoma gene 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Gland Morphogenesis Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glial Cell Proliferation Prostate Gland Growth
Pathways
Drugs
Diseases
GWAS		Height ( 19396169 19343178 19893584 18391951 20189936)
Protein-protein Interactions		5 interactors: KPNA2 PIAS1 PIAS2 PIAS4 SMAD3
Entrez ID		5324
HPRD ID		04321
Ensembl ID		ENSG00000181690
Uniprot IDs		Q6DJT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Protein Sumoylation Regulation Of Protein Sumoylation Peptidyl-lysine Modification Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Osteoblast Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Signal Transduction Evasion Or Tolerance Of Host Defenses By Virus Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Ossification Positive Regulation Of Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Nitrogen Compound Metabolic Process Signaling Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Regulation Of Signal Transduction Cell Communication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Extracellular Matrix Assembly Positive Regulation Of Smooth Muscle Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Primary MiRNA Processing Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Proteolysis RNA Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Tagcloud ?		batch calling classify cooperative driver exome fer filtering fusions h3f3a indels leukemias lmo1 mllt10 nkx2 normalization normalizations obtaining perturbations pipelines ptk2b seq skipping snv snvs ssbp2 stat5b tlx1 tpm3