SERPINB13

Description		serpin family B member 13
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Speck Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Response To UV Negative Regulation Of Endopeptidase Activity Regulation Of Proteolysis Negative Regulation Of Keratinocyte Apoptotic Process
Pathways		RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		9 interacting genes: CTSB CTSG CTSK CTSL DLG2 ELANE PLG PRSS1 PRTN3
Entrez ID		5275
HPRD ID		05118
Ensembl ID		ENSG00000197641
Uniprot IDs		A0A0A0MQW3 B7Z447 Q9UIV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidase Activity Extracellular Matrix Disassembly Serine-type Endopeptidase Activity Extracellular Matrix Endolysosome Lumen Serine-type Peptidase Activity Collagen Catabolic Process Proteolysis Collagen Metabolic Process Extracellular Space Proteoglycan Binding Hydrolase Activity Extracellular Matrix Organization Extracellular Structure Organization Extracellular Region Biological Process Involved In Interaction With Symbiont Hormone Metabolic Process Leukocyte Migration Cysteine-type Endopeptidase Activity Collagen Binding Protein Metabolic Process Endopeptidase Activity Azurophil Granule Lumen Neutrophil-mediated Killing Of Bacterium Cellular Response To Thyroid Hormone Stimulus Thyroid Hormone Generation Cysteine-type Peptidase Activity Thyroid Hormone Metabolic Process Response To Thyroid Hormone Neutrophil Mediated Immunity Lysosome Protein Processing Regulation Of Hormone Levels Fibronectin Binding Killing By Host Of Symbiont Cells Extracellular Exosome Peptide Hormone Processing Signaling Receptor Ligand Precursor Processing Macromolecule Metabolic Process Defense Response To Fungus Response To Fungus Protein Maturation Biofilm Matrix Disassembly Serpin Family Protein Binding Fusion Of Virus Membrane With Host Endosome Membrane Biosynthetic Process Of Antibacterial Peptides Active Against Gram-negative Bacteria External Side Of Plasma Membrane Regulation Of Biological Quality Leukocyte Mediated Cytotoxicity Apical Plasma Membrane
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