PFKFB2

Gene Name		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding Protein Kinase Binding
	Biological Process	Carbohydrate Metabolic Process Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Glucose Metabolic Process Glucose Catabolic Process Lactate Metabolic Process Glycolytic Process Pathogenesis Response To Glucose Dephosphorylation Positive Regulation Of Insulin Secretion Positive Regulation Of Glucokinase Activity Small Molecule Metabolic Process Carbohydrate Phosphorylation
Pathways		Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: AKT1 GCK PRKAA1 PRKAA2 PRKACA PRKCA YWHAG YWHAQ YWHAZ
Entrez ID		5208
HPRD ID		01383
Ensembl ID		ENSG00000123836
Uniprot IDs		B4DY91 O60825
PDB IDs
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Glucose Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Peptidyl-serine Phosphorylation Cellular Response To Peptide Hormone Stimulus Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Peptide Regulation Of Establishment Of Protein Localization Positive Regulation Of Signal Transduction Energy Reserve Metabolic Process Apoptotic Signaling Pathway Histone Phosphorylation Regulation Of Protein Localization Regulation Of Apoptotic Process Membrane Organization Regulation Of Cell Death Response To Peptide Hormone Positive Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Cellular Response To Organonitrogen Compound Glucose Homeostasis Response To Peptide Cellular Response To Insulin Stimulus Regulation Of Glucose Import Negative Regulation Of Glucose Import Positive Regulation Of Glycolytic Process Regulation Of Cellular Localization Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Intracellular Transport Regulation Of Signaling Cellular Response To Hormone Stimulus Regulation Of Mitochondrion Organization Negative Regulation Of Glucose Transport Response To Insulin Energy Derivation By Oxidation Of Organic Compounds Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Transport Regulation Of Protein Kinase Activity Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Response To Organonitrogen Compound Negative Regulation Of Transport Glucose Metabolic Process Chemical Homeostasis Generation Of Precursor Metabolites And Energy Negative Regulation Of Intracellular Signal Transduction Regulation Of Carbohydrate Metabolic Process
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