PEG3

Description		paternally expressed 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Autophagosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Urate levels in lean individuals ( 25811787)
Interacting Genes		7 interacting genes: APP BRCA1 LIMS1 SIAH1 SIAH2 TRAF2 USP7
Entrez ID		5178
HPRD ID		03285
Ensembl ID		ENSG00000198300
Uniprot IDs		A0A3B3IRU6 Q9GZU2
PDB IDs		4BHX
Enriched GO Terms of Interacting Partners?		Amyloid Fibril Formation Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein Modification By Small Protein Conjugation Regulation Of Signal Transduction Post-translational Protein Modification Ubiquitin Protein Ligase Activity Regulation Of Cell Communication Regulation Of Signaling Regulation Of Intracellular Signal Transduction Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Macromolecule Metabolic Process Signal Transduction Ubiquitin Conjugating Enzyme Binding Regulation Of Programmed Cell Death Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Epigenetic Regulation Of Gene Expression Protein Modification Process Protein Metabolic Process Apoptotic Process Intracellular Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Early Endosome Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Small Molecule Metabolic Process Programmed Cell Death Cell Death Tumor Necrosis Factor-mediated Signaling Pathway TORC1 Signaling Zinc Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of RNA Metabolic Process Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cell Surface Receptor Signaling Pathway P53 Binding Protein Autoubiquitination TORC2 Complex Disassembly Metal Ion Binding
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