ENPP3

Description		ectonucleotide pyrophosphatase/phosphodiesterase 3
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) Activity Phosphodiesterase I Activity Calcium Ion Binding Zinc Ion Binding Pyrophosphatase Activity Hydrolase Activity Bis(5'-adenosyl)-pentaphosphatase Activity GTP Diphosphatase Activity UTP Diphosphatase Activity Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity ATP Diphosphatase Activity Bis(5'-adenosyl)-triphosphatase Activity
	Biological Process	Basophil Activation Involved In Immune Response Pyrimidine Nucleotide Metabolic Process Phosphate-containing Compound Metabolic Process Nucleoside Triphosphate Catabolic Process Inorganic Diphosphate Transport Negative Regulation Of Mast Cell Activation Involved In Immune Response ATP Metabolic Process Negative Regulation Of Inflammatory Response Phosphate Ion Homeostasis Negative Regulation Of Mast Cell Proliferation
Pathways		Vitamin B5 (pantothenate) metabolism
Drugs
Diseases
GWAS		Body mass index (change over time) in lung cancer ( 28044437) L-arginine levels ( 25245031) Osteoarthritis of the hand ( 28855172) Phosphorus levels ( 29403010) Resistant hypertension ( 31545351) Response to fenofibrate (adiponectin levels) ( 23149075) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 32499647)
Interacting Genes		1 interacting genes: CNKSR1
Entrez ID		5169
HPRD ID		03715
Ensembl ID		ENSG00000154269
Uniprot IDs		F8W6H5 O14638
PDB IDs		6C01 6C02
Enriched GO Terms of Interacting Partners?
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