ASB4

Description		ankyrin repeat and SOCS box containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cul2-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Protein Autoubiquitination Positive Regulation Of Vasculogenesis
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Metabolite levels ( 23823483) Middle childhood and early adolescence aggressive behavior ( 26087016)
Novel Interacting Genes		1 novel interacting genes: AKAP9
Interacting Genes		3 interacting genes: HIF1AN ID2 UBE2D1
Entrez ID		51666
HPRD ID		05770
Ensembl ID		ENSG00000005981
Uniprot IDs		Q9Y574
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of B Cell Differentiation Negative Regulation Of Dopaminergic Neuron Differentiation Transmembrane Transporter Binding Peyer's Patch Development Bundle Of His Development Transcription Corepressor Activity Negative Regulation Of DNA-templated Transcription Enucleate Erythrocyte Differentiation Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Negative Regulation Of Transcription By RNA Polymerase II Endodermal Digestive Tract Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mucosa-associated Lymphoid Tissue Development Negative Regulation Of RNA Biosynthetic Process Thigmotaxis Maintenance Of Centrosome Location Potassium Channel Activator Activity Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Dendritic Branch Extrinsic Component Of Postsynaptic Density Membrane Ankyrin Repeat Binding [protein]-asparagine 3-dioxygenase Activity Peptidyl-aspartic Acid 3-dioxygenase Activity Carboxylic Acid Binding Peptidyl-histidine Dioxygenase Activity Oxygen Sensor Activity Negative Regulation Of RNA Metabolic Process Potassium Channel Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Locomotor Rhythm Regulation Of Dopaminergic Neuron Differentiation Membranous Septum Morphogenesis Positive Regulation Of Astrocyte Differentiation Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Vasculogenesis Ventricular Cardiac Muscle Tissue Development Negative Regulation Of Oligodendrocyte Differentiation Response To Lithium Ion Positive Regulation Of Macrophage Differentiation Embryonic Digestive Tract Morphogenesis Mammary Gland Epithelial Cell Differentiation Cellular Response To Lithium Ion Mammary Gland Alveolus Development Mammary Gland Epithelial Cell Proliferation White Fat Cell Differentiation Positive Regulation Of Protein Polyubiquitination Regulation Of Golgi Organization Regulation Of Vasculogenesis Natural Killer Cell Differentiation Cell Morphogenesis Involved In Neuron Differentiation
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