SF3B6

Description		splicing factor 3b subunit 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Blastocyst Formation MRNA Processing RNA Splicing U2-type Prespliceosome Assembly
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP CEBPA ERBB3 RPL4 SF3B1 U2AF2
Entrez ID		51639
HPRD ID		09702
Ensembl ID		ENSG00000115128
Uniprot IDs		Q9Y3B4
PDB IDs		2F9D 2F9J 2FHO 3LQV 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6Y53 6Y5Q 7ABG 7ABH 7ABI 7DVQ 7Q4O 8H6E 8H6J 8H6K 8H6L 8I0P 8I0R 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E
Enriched GO Terms of Interacting Partners?		U2-type Prespliceosome Acetylcholine Receptor Activator Activity Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Gene Expression Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Protein Heterodimerization Activity Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Macromolecule Biosynthetic Process CHOP-C/EBP Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity Spliceosomal Complex Assembly Poly-pyrimidine Tract Binding U11/U12 SnRNP Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Developmental Maturation Axon Midline Choice Point Recognition Intracellular Signaling Cassette NMDA Selective Glutamate Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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