PDHA2

Name	pyruvate dehydrogenase E1 subunit alpha 2
Structure	No pdb structure
Interactors	2 interactors: MEOX2 PDHB
GO Annotations	Cellular Component	Nucleus Nucleolus Mitochondrion Mitochondrial Matrix Pyruvate Dehydrogenase Complex
	Molecular Function	Pyruvate Dehydrogenase (acetyl-transferring) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, Disulfide As Acceptor Metal Ion Binding
	Biological Process	Glucose Metabolic Process Pyruvate Decarboxylation To Acetyl-CoA Tricarboxylic Acid Cycle
Pathways	Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid PDH complex synthesizes acetyl-CoA from PYR
Drugs	NADH
GWAS	Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644 ) Metabolite levels ( 23823483 ) Triacylglyceride levels ( 31551469 )
Entrez ID	5161
HPRD ID	01531
Ensembl ID	ENSG00000163114
Uniprot IDs	P29803
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Somite Specification Pyruvate Decarboxylation To Acetyl-CoA Pyruvate Dehydrogenase Complex Pyruvate Dehydrogenase (acetyl-transferring) Activity Segment Specification Somite Development Acetyl-CoA Biosynthetic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Acetyl-CoA Metabolic Process Tricarboxylic Acid Cycle Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Embryonic Pattern Specification Skeletal Muscle Tissue Development Pyruvate Metabolic Process Negative Regulation Of Endothelial Cell Migration