ZC3HC1

Description		zinc finger C3HC-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Nuclear Membrane Nuclear Pore Nuclear Basket
	Molecular Function	Protein Binding Zinc Ion Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Cell Division
Pathways		Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Coronary artery disease ( 24262325 26343387 33020668 32469254 29212778) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Diastolic blood pressure ( 27618452 27841878) Eosinophil count ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Myocardial infarction ( 33532862 26343387) Neutrophil count ( 32888494) Parental lifespan ( 30642433) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Red cell distribution width ( 32888494) Systolic blood pressure ( 28739976 27841878 27618452) White blood cell count ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		11 interacting genes: ALK APP CUL1 MAPK3 PDPK1 TNFSF11 TPR TRIM55 TRIM63 TSC22D1 YWHAE
Entrez ID		51530
HPRD ID		11390
Ensembl ID		ENSG00000091732
Uniprot IDs		C9J0I9 Q86WB0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Intracellular Signal Transduction Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Response To Epidermal Growth Factor Intracellular Signaling Cassette Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Response To Stress Peptidyl-tyrosine Autophosphorylation Response To Cytokine Response To Peptide Protein Modification Process Identical Protein Binding Regulation Of Non-canonical NF-kappaB Signal Transduction Response To Growth Factor Immune System Process Protein Autophosphorylation Negative Regulation Of Catabolic Process Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Defense Response Positive Regulation Of Transport Regulation Of Calcium Ion Transmembrane Transport Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Cell Development Positive Regulation Of Protein Localization Calcium-mediated Signaling Positive Regulation Of Defense Response Positive Regulation Of Inflammatory Response Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Regulation Of Immune System Process Regulation Of Transport Positive Regulation Of ERK1 And ERK2 Cascade Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Cellular Localization Negative Regulation Of Immune System Process Regulation Of Protein Export From Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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