HIKESHI

Description		heat shock protein nuclear import factor hikeshi
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Hsp70 Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Import Into Nucleus Golgi Organization Protein Transport Lung Development Cellular Response To Heat
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: ABLIM3 APP OTX2
Entrez ID		51501
HPRD ID		13701
Ensembl ID		ENSG00000149196
Uniprot IDs		Q53FT3
PDB IDs		3WVZ 3WW0
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Growth Cone Lipoprotein Particle Cell Projection Organization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Positive Regulation Of DNA-templated Transcription Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Establishment Of Protein Localization NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of RNA Metabolic Process Axon Choice Point Recognition Positive Regulation Of Gastrulation Heparan Sulfate Binding Signaling Receptor Activator Activity Eukaryotic Initiation Factor 4E Binding Peptidase Activator Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Manganese Ion Antifungal Humoral Response Nuclear Envelope Lumen Primitive Streak Formation
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