HACD3

Description		3-hydroxyacyl-CoA dehydratase 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Focal Adhesion Membrane Nuclear Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Lyase Activity 3-hydroxyacyl-CoA Dehydratase Activity Enzyme Binding Very-long-chain (3R)-3-hydroxyacyl-CoA Dehydratase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Canonical NF-kappaB Signal Transduction JNK Cascade Small GTPase-mediated Signal Transduction Rho Protein Signal Transduction Rac Protein Signal Transduction Sphingolipid Biosynthetic Process Fatty Acid Elongation Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Intracellular Signal Transduction
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hemoglobin levels ( 32327693)
Novel Interacting Genes		1 novel interacting genes: DPCD
Interacting Genes		3 interacting genes: HMGB2 NEAT1 RAC1
Entrez ID		51495
HPRD ID		11037
Ensembl ID		ENSG00000074696
Uniprot IDs		H3BRL8 Q9P035
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Response To Molecule Of Bacterial Origin DNA Geometric Change Response To Lipopolysaccharide DNA Topological Change Positive Regulation Of Epithelial Cell Proliferation Non-sequence-specific DNA Binding, Bending Supercoiled DNA Binding Nucleus Organization Cell Motility Spermatid Nucleus Differentiation Chemotaxis Negative Regulation Of Gene Expression Kinocilium Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Bicellular Tight Junction Assembly Negative Regulation Of Interleukin-23 Production Regulation Of Interleukin-23 Production Regulation Of Ovarian Follicle Development Regulation Of ERK5 Cascade G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Rho GDP-dissociation Inhibitor Binding Auditory Receptor Cell Morphogenesis Angiotensin-activated Signaling Pathway Involved In Heart Process Regulation Of Neuron Maturation Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Embryonic Olfactory Bulb Interneuron Precursor Migration Thioesterase Binding Erythrocyte Enucleation Cerebral Cortex GABAergic Interneuron Development Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Cell Adhesion Involved In Heart Morphogenesis Engulfment Of Apoptotic Cell Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Tangential Migration From The Subventricular Zone To The Olfactory Bulb Third Ventricle Development RISC Complex Binding Positive Regulation Of Synoviocyte Proliferation Paraspeckles Positive Regulation Of MiRNA Catabolic Process Regulation Of MRNA Export From Nucleus MiRNA Inhibitor Activity Via Base-pairing LncRNA-mediated Post-transcriptional Gene Silencing Locomotion Regulation Of Epithelial Cell Proliferation RAGE Receptor Binding Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Receptor Clustering Negative Regulation Of Fibroblast Migration Midbrain Dopaminergic Neuron Differentiation
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