PRRX2

Description		paired related homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Response to exercise (triglyceride level interaction) ( 26491034)
Novel Interacting Genes		2 novel interacting genes: CASP8 NUP214
Interacting Genes		1 interacting genes: SOX10
Entrez ID		51450
HPRD ID		05244
Ensembl ID		ENSG00000167157
Uniprot IDs		A0A140VJS2 Q99811
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Anesthetic Ripoptosome Embryo Development Ending In Birth Or Egg Hatching Death Effector Domain Binding Multicellular Organism Development Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development CD95 Death-inducing Signaling Complex Chordate Embryonic Development Mitochondrial Outer Membrane Lacrimal Gland Development Cellular Response To Progesterone Stimulus Cytoplasmic Side Of Nuclear Pore Death-inducing Signaling Complex Positive Regulation Of Pyroptotic Inflammatory Response Positive Regulation Of Cell Development Self Proteolysis Response To Cobalt Ion TRAIL-activated Apoptotic Signaling Pathway Central Nervous System Myelination Negative Regulation Of Schwann Cell Proliferation Enteric Nervous System Development Nuclear Export Signal Receptor Activity Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Macrophage Differentiation Death Receptor Binding Negative Regulation Of Necroptotic Process Negative Regulation Of Programmed Necrotic Cell Death Digestive Tract Morphogenesis Pigment Cell Differentiation Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Melanocyte Differentiation Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Regulation Of Macrophage Differentiation Execution Phase Of Apoptosis Cell Differentiation Involved In Embryonic Placenta Development Oligodendrocyte Development Peripheral Nervous System Development DNA-binding Transcription Activator Activity Positive Regulation Of Neuroblast Proliferation Regulation Of Necroptotic Process Tumor Necrosis Factor Receptor Binding Protein Export From Nucleus Response To Progesterone Response To Lipid Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macrophage Differentiation Regulation Of Cell Development Pyroptotic Inflammatory Response
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