IP6K2

Gene Name		inositol hexakisphosphate kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Inositol Hexakisphosphate 5-kinase Activity ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Inositol Hexakisphosphate 1-kinase Activity Inositol Hexakisphosphate 3-kinase Activity
	Biological Process	Phosphate Ion Transport Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Type I Interferon Signaling Pathway
Pathways		Synthesis of IPs in the nucleus Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Inositol phosphate metabolism
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		4 interactors: HSP90AA1 MEOX2 PLSCR1 RBPMS
Entrez ID		51447
HPRD ID		07380
Ensembl ID		ENSG00000068745
Uniprot IDs		B2RCP4 Q9UHH9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Protein Import Into Mitochondrial Outer Membrane Somite Specification Phosphatidylserine Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phospholipid Scrambling Regulation Of Nitrogen Compound Metabolic Process Chaperone-mediated Protein Complex Assembly Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus Segment Specification Nitrogen Compound Metabolic Process Response To Interferon-beta Protein Refolding Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Immune Response Nitric Oxide Metabolic Process Phosphatidylserine Metabolic Process Regulation Of Cellular Response To Heat Reactive Nitrogen Species Metabolic Process Positive Regulation Of ATPase Activity Regulation Of Mast Cell Activation Regulation Of Nitric-oxide Synthase Activity Acute-phase Response Regulation Of ATPase Activity Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Membrane Organization Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Immune Response Negative Regulation Of Viral Genome Replication Transcription From RNA Polymerase II Promoter Positive Regulation Of Immune System Process Intracellular Protein Transmembrane Transport RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Metabolic Process Protein Transmembrane Transport Mitochondrial Membrane Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Targeting To Mitochondrion Cellular Response To Heat Cell Death Gene Expression
Tagcloud ?		actions apoptotic atm cascade ck2 cochaperone diphosphoinositol hexakisphosphate inositol ip6ks ip7 kinases linking pentakisphosphate phosphoinositide pikks pkcs pyrophosphates require serine stabilized stabilizing stimulates tel2 thereby tti1 tti2 ttt whose