IP6K2

Description		inositol hexakisphosphate kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cell Junction
	Molecular Function	Nucleotide Binding Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Diphosphoinositol Pentakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Diphosphoinositol Tetrakisphosphate Kinase Activity Flavonoid Binding
	Biological Process	Lipid Metabolic Process Negative Regulation Of Cell Growth Inositol Phosphate Biosynthetic Process Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Protein Stabilization Organophosphate Biosynthetic Process Cellular Response To Flavonoid
Pathways		Synthesis of IPs in the nucleus Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878) Eosinophil count ( 32888494) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 23128233 28067908) Lipoprotein (a) levels ( 33730874) Morning person ( 30696823) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		1 novel interacting genes: QRICH1
Interacting Genes		7 interacting genes: HSP90AA1 LNX2 MEOX2 PLOD3 PLSCR1 RBPMS ZBTB2
Entrez ID		51447
HPRD ID		07380
Ensembl ID		ENSG00000068745
Uniprot IDs		B2RCP4 C9JRM0 Q9UHH9
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Unfolded Protein Rho GDP-dissociation Inhibitor Binding CTP Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process DATP Binding Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Hydroxylysine Biosynthetic Process Procollagen Glucosyltransferase Activity Procollagen-lysine 5-dioxygenase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Basement Membrane Assembly Procollagen Galactosyltransferase Activity MRNA CDS Binding
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