CRIM1

Description		cysteine rich transmembrane BMP regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Enzyme Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Insulin-like Growth Factor Receptor Activity PDZ Domain Binding
	Biological Process	Nervous System Development Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Osteoblast Differentiation Insulin-like Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anthropometric traits ( 19260139) Bone mineral density (total hip) ( 29883787) Central corneal thickness ( 32528159) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Height ( 25282103 25429064 33713608 31562340) Hip circumference adjusted for BMI ( 34021172) IgE levels in asthmatics ( 23967269) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) QRS duration ( 30012220 27577874) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: ATXN7 CACNA1A DYRK1A MTDH
Entrez ID		51232
HPRD ID		08392
Ensembl ID		ENSG00000150938
Uniprot IDs		Q9NZV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Or Depolymerization Histone H3T45 Kinase Activity Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Regulation Of RNA Splicing Regulation Of Microtubule-based Process Negative Regulation Of Heterochromatin Formation Regulation Of Neurofibrillary Tangle Assembly Splicing Factor Binding Intercellular Canaliculus Transcription Coactivator Activity RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Regulation Of Heterochromatin Formation Neurofilament High Voltage-gated Calcium Channel Activity Negative Regulation Of Microtubule Polymerization Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of DNA-templated Transcription Regulation Of Supramolecular Fiber Organization Calcium Ion Import Across Plasma Membrane Voltage-gated Calcium Channel Complex Calcium Ion Import Into Cytosol Tau-protein Kinase Activity Regulation Of Cellular Response To Stress Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cytoskeleton Organization Regulation Of Chromatin Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Inclusion Body Assembly Positive Regulation Of RNA Metabolic Process SAGA Complex Transcription Factor TFTC Complex Negative Regulation Of RNA Splicing Protein Serine/threonine/tyrosine Kinase Activity
Tagcloud ?