CRIM1

Gene Name		cysteine rich transmembrane BMP regulator 1 (chordin-like)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Insulin-like Growth Factor-activated Receptor Activity Insulin-like Growth Factor Binding PDZ Domain Binding
	Biological Process	Regulation Of Cell Growth Nervous System Development Negative Regulation Of Endopeptidase Activity Insulin-like Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 19260139) Ventricular conduction ( 21076409)
Protein-protein Interactions		2 interactors: ATXN7 CACNA1A
Entrez ID		51232
HPRD ID		08392
Ensembl ID		ENSG00000150938
Uniprot IDs		Q9NZV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Molecular Layer Development Vestibular Nucleus Development Musculoskeletal Movement, Spinal Reflex Action Cerebellum Maturation Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Histone Deubiquitination Reflex Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Behavioral Response To Pain Neuromuscular Synaptic Transmission Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neurotransmitter Metabolic Process Neurological System Process Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Calcium Ion Import Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Response To Pain Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Sulfur Amino Acid Metabolic Process Musculoskeletal Movement Calcium Ion-dependent Exocytosis Anion Homeostasis Spinal Cord Motor Neuron Differentiation Adult Walking Behavior Cerebellum Morphogenesis Receptor Clustering Neural Nucleus Development Hindbrain Morphogenesis Regulation Of Calcium Ion-dependent Exocytosis Transmission Of Nerve Impulse Ventral Spinal Cord Development Acid Secretion Cell Differentiation In Spinal Cord Cerebellar Cortex Development
Tagcloud ?		allele cmv conditional cre crossing deleted deltaflox developmentally digit engineered exons flanking flox germline kst264 lethality loxp null penetrance perinatal phenotypes pleimorphic resource syndactyly unidirectional valuable varying