CLDN18

Description		claudin 18
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Lateral Plasma Membrane Tight Junction Anchoring Junction
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Localization To Nucleus Organ Growth Epithelial Fluid Transport Response To Ethanol Negative Regulation Of Bone Resorption Lung Alveolus Development Digestive Tract Development Epithelial Cell Proliferation Bicellular Tight Junction Assembly Cellular Response To Estrogen Stimulus Tight Junction Organization Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Osteoclast Development
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Metabolite levels ( 23823483)
Novel Interacting Genes		1 novel interacting genes: STAG1
Interacting Genes		2 interacting genes: EHHADH PMP22
Entrez ID		51208
HPRD ID		13066
Ensembl ID		ENSG00000066405
Uniprot IDs		P56856
PDB IDs
Enriched GO Terms of Interacting Partners?		Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Delta(3)-delta(2)-enoyl-CoA Isomerase Activity 3-hydroxyacyl-CoA Dehydratase Activity Compact Myelin Establishment Of Mitotic Sister Chromatid Cohesion Cohesin Complex Establishment Of Sister Chromatid Cohesion Mitotic Cohesin Complex Bleb Assembly Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Myelin Assembly NAD+ Binding Peripheral Nervous System Development Long-chain Fatty Acid Biosynthetic Process Mitotic Spindle Pole Unsaturated Fatty Acid Biosynthetic Process Sister Chromatid Cohesion Mitotic Spindle Assembly
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