SDF4

Name	stromal cell derived factor 4
Structure	No pdb structure
Interactors	12 interactors: ANXA7 APP CDKN1A NR1I2 RAP1B RCC1 RPA2 SMN1 SNCA TK1 TTR ZNF512B
GO Annotations	Cellular Component	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Golgi Lumen Plasma Membrane Membrane Bleb Cell Projection Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Exocytosis UV Protection Calcium-ion Regulated Exocytosis Cerebellum Development Fat Cell Differentiation Response To Ethanol Zymogen Granule Exocytosis Maintenance Of Synapse Structure
GWAS	Blond vs. brown/black hair color ( 30531825 ) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007 ) Medication use (thyroid preparations) ( 31015401 )
Entrez ID	51150
HPRD ID	13113
Ensembl ID	ENSG00000078808
Uniprot IDs	A0A5F9UJX7 Q9BRK5
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Protein Tetramerization Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Presynapse Assembly Protein-containing Complex Molecular Function Activator Activity Regulation Of Neurotransmitter Uptake Protein Serine/threonine Kinase Binding Positive Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Copper Ion Nuclear Body Mitotic G1/S Transition Checkpoint Signaling Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of MiRNA Transcription Amyloid Fibril Formation Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Regulation Of Mitotic Cell Cycle Negative Regulation Of Exocytosis Protein Sequestering Activity Protein Kinase Inhibitor Activity Amyloid-beta Complex Growth Cone Lamellipodium Protein Complex Oligomerization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Synapse Organization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Regulation Of Cell Junction Assembly Macrophage Activation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Mitotic DNA Damage Checkpoint Signaling Response To Metal Ion Acetylcholine Receptor Activator Activity Positive Regulation Of Phosphate Metabolic Process Response To Light Stimulus Regulation Of MiRNA Transcription Lipoprotein Particle Positive Regulation Of Protein Import Mitotic DNA Integrity Checkpoint Signaling