GLRX2

Description		glutaredoxin 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Protein-disulfide Reductase Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Regulation Of DNA-templated Transcription Glutathione Metabolic Process Apoptotic Process Response To Temperature Stimulus Regulation Of Signal Transduction Cell Differentiation DNA Protection Cell Redox Homeostasis Response To Redox State
Pathways
Drugs		Glutathione
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: DENND1B NUTF2
Interacting Genes		4 interacting genes: DCXR ELF5 FBXO7 TXNRD1
Entrez ID		51022
HPRD ID		12112
Ensembl ID		ENSG00000023572
Uniprot IDs		Q9NS18
PDB IDs		2CQ9 2FLS 2HT9
Enriched GO Terms of Interacting Partners?		NADPH Peroxidase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite L-xylulose Reductase (NADPH) Activity Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Ectodermal Cell Fate Commitment Xylulose Metabolic Process Protein Localization To Nuclear Pore Lewy Body Core D-xylose Metabolic Process Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, NAD(P) As Acceptor Oxidoreductase Activity, Acting On CH-OH Group Of Donors D-glucuronate Catabolic Process D-glucuronate Catabolic Process To D-xylulose 5-phosphate Nuclear Pore Central Transport Channel Thioredoxin-disulfide Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Carbonyl Reductase (NADPH) Activity Positive Regulation Of T-helper 2 Cell Cytokine Production Pentose Metabolic Process
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