CDON

Description		cell adhesion associated, oncogene regulated
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding Coreceptor Activity
	Biological Process	Cell Fate Specification Positive Regulation Of Neuroblast Proliferation Lens Development In Camera-type Eye Cell Adhesion Smoothened Signaling Pathway Nervous System Development Neuroblast Proliferation Skeletal Muscle Tissue Development Myoblast Fusion Anterior/posterior Pattern Specification Embryonic Body Morphogenesis Skeletal Muscle Satellite Cell Differentiation Central Nervous System Neuron Differentiation Cerebral Cortex Development Neuron Differentiation Positive Regulation Of MAPK Cascade Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Morphogenesis Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Small GTPase Mediated Signal Transduction Striated Muscle Cell Differentiation Embryonic Retina Morphogenesis In Camera-type Eye Neural Precursor Cell Proliferation Negative Regulation Of Biomineral Tissue Development Cellular Response To Vitamin D Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion
Pathways		Myogenesis Myogenesis Ligand-receptor interactions Activation of SMO
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 22881374) Blood protein levels ( 30072576) Cerebral white matter volume ( 31530798) Height ( 31562340) Lung function (FEV1) ( 28166213) Mild to moderate chronic kidney disease ( 31178898) Primary tooth development (time to first tooth eruption) ( 23704328) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Novel Interacting Genes		1 novel interacting genes: NRGN
Interacting Genes		5 interacting genes: ABL1 BOC CDH15 CDH2 CTNNB1
Entrez ID		50937
HPRD ID		16372
Ensembl ID		ENSG00000064309
Uniprot IDs		A0A804HL16 Q4KMG0
PDB IDs		3D1M 3N1F 3N1Q
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Catenin Complex Cell-cell Adhesion Mediated By Cadherin Adherens Junction Organization Positive Regulation Of Blood Vessel Branching Cell Adhesion Detection Of Muscle Stretch Regulation Of Blood Vessel Branching Fascia Adherens Glial Cell Differentiation Alpha-catenin Binding Myoblast Proliferation Cell-cell Junction Assembly Synaptic Vesicle Clustering Cell-cell Junction Organization Adherens Junction Apicolateral Plasma Membrane Cell Morphogenesis Response To Muscle Stretch Telencephalon Development Positive Regulation Of Morphogenesis Of An Epithelium Neuroepithelial Cell Differentiation Cell Junction Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Synapse Organization T Cell Differentiation In Thymus Regulation Of Long-term Synaptic Potentiation Cell Migration Detection Of Mechanical Stimulus Intercalated Disc Thymus Development Cadherin Binding Regulation Of Wnt Signaling Pathway Regulation Of Morphogenesis Of A Branching Structure System Development Cell Motility Epidermal Growth Factor Receptor Signaling Pathway Epithelial Cell Differentiation Enzyme Binding Positive Regulation Of Neuron Apoptotic Process Regulation Of Morphogenesis Of An Epithelium ERBB Signaling Pathway Protein Kinase Binding Protein Localization To Cytoplasmic Microtubule Plus-end Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of MAPK Cascade Cell Junction Organization Apical Part Of Cell Regulation Of Fibroblast Proliferation
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