IL21R

Description		interleukin 21 receptor
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Interleukin-21 Receptor Activity Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Protein Binding
	Biological Process	Cytokine-mediated Signaling Pathway Natural Killer Cell Activation Interleukin-21-mediated Signaling Pathway
Pathways		Interleukin-21 signaling
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Bone mineral density ( 19874204) Leprosy ( 27976721) Mosquito bite size ( 28199695) Primary biliary cholangitis ( 26394269 28425483) Self-reported allergy ( 23817569) Serum IgE levels ( 25488688)
Interacting Genes		3 interacting genes: AQP1 IL21 JAK1
Entrez ID		50615
HPRD ID		05649
Ensembl ID		ENSG00000103522
Uniprot IDs		Q9HBE5
PDB IDs		3TGX 4NZD 6PLH 7KQ7 8ENT
Enriched GO Terms of Interacting Partners?		Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Cellular Response To Virus Positive Regulation Of Vasculature Development Metanephric Glomerulus Vasculature Development Positive Regulation Of Angiogenesis Positive Regulation Of Saliva Secretion Response To Other Organism Response To External Biotic Stimulus Cellular Response To Mercury Ion Positive Regulation Of Developmental Process Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Glycerol Transmembrane Transporter Activity Corticotropin Secretion Regulation Of Vasculature Development Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Ankyrin-1 Complex Regulation Of Angiogenesis Cerebrospinal Fluid Secretion Renal Water Absorption Carbon Dioxide Transmembrane Transporter Activity Glomerulus Vasculature Development Glycerol Transmembrane Transport Water Transmembrane Transporter Activity Regulation Of Multicellular Organismal Development Positive Regulation Of Multicellular Organismal Process Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Intracellularly CGMP-activated Cation Channel Activity Carbon Dioxide Transmembrane Transport Lipid Digestion Intracellular Water Homeostasis Pancreatic Juice Secretion Positive Regulation Of Cell-cell Adhesion Interleukin-11-mediated Signaling Pathway Interleukin-4-mediated Signaling Pathway Protein Phosphorylation Interleukin-2 Receptor Binding Tyrosine Phosphorylation Of STAT Protein Renal Water Transport Regulation Of Saliva Secretion Interleukin-9-mediated Signaling Pathway CCR5 Chemokine Receptor Binding Interleukin-7-mediated Signaling Pathway Ammonium Channel Activity Polyol Transmembrane Transport
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