P2RY2

Gene Name		purinergic receptor P2Y, G-protein coupled, 2
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Receptor Activity G-protein Coupled Purinergic Nucleotide Receptor Activity
	Biological Process	Cellular Ion Homeostasis Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Purinergic Nucleotide Receptor Signaling Pathway Regulation Of Vasodilation Positive Regulation Of Mucus Secretion
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Nucleotide-like (purinergic) receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding P2Y receptors
Drugs
Diseases
GWAS		Body mass index (asthmatics) ( 23517042) Insomnia (caffeine-induced) ( 22754043)
Protein-protein Interactions		7 interactors: APP CD47 ITGAV ITGB3 ITGB5 KDR SRC
Entrez ID		5029
HPRD ID		02499
Ensembl ID		ENSG00000175591
Uniprot IDs		P41231
PDB IDs		1Z8E
Enriched GO Terms of Interacting Partners?		Integrin-mediated Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Immune System Process Cell Adhesion Locomotion Regulation Of Body Fluid Levels Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Substrate Adhesion-dependent Cell Spreading Wound Healing Cell-substrate Adhesion Leukocyte Migration Movement Of Cell Or Subcellular Component Response To Wounding Cell Surface Receptor Signaling Pathway Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of Locomotion Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Cell Adhesion Axon Guidance Negative Regulation Of Lipoprotein Metabolic Process Formation Of Primary Germ Layer Regulation Of Lipoprotein Metabolic Process Stress Fiber Assembly Anatomical Structure Morphogenesis Regulation Of Epithelial Cell Migration Single Organismal Cell-cell Adhesion Axonogenesis Cell Growth Negative Regulation Of Macrophage Derived Foam Cell Differentiation Viral Process Regulation Of Receptor Biosynthetic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell-matrix Adhesion Regulation Of Cell Migration Negative Regulation Of Lipid Storage Negative Chemotaxis Chemotaxis Regulation Of Cell Adhesion
Tagcloud ?		10d a2a adenosine adora1 adora2a adora3 b4 c5ar1 calving chemoattractant deaminase holstein hydroxybutyrate leukotriene ltb4r mcal multiparous nonesterified nucleotidase p2y parturition peripartal pmnl ptafr purinergic sell selplg slc29a1 slc29a2