ARK2C

Description		arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C
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GO Annotations	Cellular Component	Nucleus Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Axonogenesis Motor Neuron Axon Guidance Protein Catabolic Process Positive Regulation Of BMP Signaling Pathway Forelimb Morphogenesis Limb Development Innervation Muscle Structure Development
Pathways
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: UBC UBE2D1 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W
Entrez ID		494470
HPRD ID
Ensembl ID		ENSG00000141622
Uniprot IDs		A0A059NXK6 Q6ZSG1
PDB IDs		5D0I 5D0K 5D0M 5ULH 5ULK 7R70 7R71
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Monoubiquitination Post-translational Protein Modification Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein K11-linked Ubiquitination Protein Modification Process Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteolysis ATP Binding Protein Metabolic Process Nucleotide Binding Transferase Activity Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling Protein K63-linked Ubiquitination TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Regulation Of TOR Signaling Proteasomal Protein Catabolic Process Macromolecule Metabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Protein Catabolic Process Cellular Response To Nutrient Levels Nucleoplasm Ubiquitin Protein Ligase Binding Nucleus Negative Regulation Of BMP Signaling Pathway Antiviral Innate Immune Response Positive Regulation Of Protein Ubiquitination Response To Nutrient Levels Ubiquitin Ligase Complex Regulation Of BMP Signaling Pathway DNA Repair UBC13-MMS2 Complex Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Post-translational Protein Modification ISG15 Transferase Activity Ubiquitin Conjugating Enzyme Complex
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