NRTN

Name	neurturin
Structure
Novel Interactors	1 novel interactors: NFIX
Interactors	3 interactors: GFRA1 GFRA2 RET
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding Heparan Sulfate Binding
	Biological Process	MAPK Cascade Neural Crest Cell Migration Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Nerve Development Neuron Projection Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Via STAT
Pathways	NCAM1 interactions RAF/MAP kinase cascade RET signaling
GWAS	Advanced age-related macular degeneration ( 26691988 ) Chronotype ( 30696823 ) N-glycan levels ( 21203500 21908519 31163085 )
Entrez ID	4902
HPRD ID	03604
Ensembl ID	ENSG00000171119
Uniprot IDs	Q99748
PDB IDs	5MR4 5MR5 5MR9 5NMZ 6GL7 6Q2O 6Q2R
GO Terms Enriched among Interactors ?	Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Glial Cell-derived Neurotrophic Factor Receptor Activity Receptor Complex Extrinsic Component Of Membrane Plasma Membrane Protein Complex Signaling Receptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Enzyme-linked Receptor Protein Signaling Pathway Side Of Membrane Posterior Midgut Development Kidney Development Peyer's Patch Morphogenesis Positive Regulation Of Metanephric Glomerulus Development System Development Neurotrophin Receptor Activity Ureter Maturation GDF15-GFRAL Signaling Pathway Positive Regulation Of Glomerulus Development Heparan Sulfate Binding Lymphocyte Migration Into Lymphoid Organs External Side Of Plasma Membrane Positive Regulation Of Kidney Development Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Neuron Differentiation Positive Regulation Of Cell Size Enteric Nervous System Development Axon Neuron Cell-cell Adhesion Response To Pain Neuron Projection Development Positive Regulation Of Cell Adhesion Mediated By Integrin Cell Surface Receptor Signaling Pathway Embryonic Epithelial Tube Formation Neurotrophin Signaling Pathway Neuron Maturation Epithelial Tube Formation Membrane Protein Proteolysis Regulation Of Kidney Development Metanephros Development