NPR2

Description		natriuretic peptide receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cilium Membrane Neuron Projection Synapse
	Molecular Function	Nucleotide Binding Guanylate Cyclase Activity Protein Kinase Activity Protein Binding ATP Binding GTP Binding Lyase Activity Phosphorus-oxygen Lyase Activity Natriuretic Peptide Receptor Activity Peptide Hormone Binding Hormone Binding Identical Protein Binding
	Biological Process	MAPK Cascade Ossification Ovarian Follicle Development Cumulus Cell Differentiation Blood Vessel Development Vasculogenesis Lymph Vessel Development Endochondral Ossification Startle Response Blood Vessel Remodeling Chondrocyte Differentiation Growth Plate Cartilage Development CGMP Biosynthetic Process Vacuole Organization Receptor Guanylyl Cyclase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Chemical Synaptic Transmission Germ Cell Development Spermatogenesis Single Fertilization Axonogenesis Sensory Perception Of Sound Blood Circulation Regulation Of Blood Pressure Cyclic Nucleotide Biosynthetic Process Response To Wounding Response To Hormone Neuronal Action Potential Vestibulocochlear Nerve Development Vestibulocochlear Nerve Maturation Nerve Development Female Genitalia Development Response To Luteinizing Hormone Limb Morphogenesis Genitalia Morphogenesis Multicellular Organism Growth Gastric Emptying Intracellular Signal Transduction Chondrocyte Proliferation Post-anal Tail Morphogenesis CGMP Metabolic Process Digestive Tract Morphogenesis Digestive Tract Development Oocyte Development Collateral Sprouting Smooth Muscle Tissue Development White Fat Cell Differentiation Cartilage Development Chromosome Organization Meiotic Cell Cycle Neuron Apoptotic Process Negative Regulation Of Meiotic Cell Cycle Limb Development Bone Development Axonogenesis Involved In Innervation Activation Of Meiosis Involved In Egg Activation Vascular Wound Healing C-di-GMP Signaling Cellular Response To CGMP Response To Fibroblast Growth Factor Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Execution Phase Of Apoptosis Bone Growth Negative Regulation Of Oocyte Maturation Cellular Response To Peptide Response To Salt Meiotic Cell Cycle Process Involved In Oocyte Maturation
Pathways		Physiological factors
Drugs		Erythrityl tetranitrate Nesiritide Vosoritide
Diseases		Acromesomelic dysplasia, Maroteaux type
GWAS		Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Height ( 31562340)
Novel Interacting Genes		1 novel interacting genes: DNAI1
Interacting Genes		3 interacting genes: NPPA NPPB NPPC
Entrez ID		4882
HPRD ID		00166
Ensembl ID		ENSG00000159899
Uniprot IDs		P20594
PDB IDs
Enriched GO Terms of Interacting Partners?		Hormone Receptor Binding Guanylate Cyclase Activator Activity Receptor Guanylyl Cyclase Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Cyclic Nucleotide Biosynthetic Process CGMP-mediated Signaling Cyclic Purine Nucleotide Metabolic Process Positive Regulation Of CGMP-mediated Signaling Hormone Activity Purine Ribonucleotide Biosynthetic Process Enzyme-linked Receptor Protein Signaling Pathway Blood Vessel Diameter Maintenance Ribose Phosphate Biosynthetic Process Regulation Of Tube Size Regulation Of CGMP-mediated Signaling Purine Nucleotide Biosynthetic Process Cardiac Conduction System Development Nucleotide Biosynthetic Process Protein Folding Purine-containing Compound Biosynthetic Process Negative Regulation Of Systemic Arterial Blood Pressure Vascular Process In Circulatory System Nucleoside Phosphate Biosynthetic Process Purine Ribonucleotide Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Circulatory System Process Purine Nucleotide Metabolic Process Regulation Of Vascular Permeability Negative Regulation Of Blood Pressure Signaling Receptor Binding Nucleotide Metabolic Process Vasodilation Carbohydrate Derivative Biosynthetic Process Cardiac Muscle Tissue Development Purine-containing Compound Metabolic Process Organophosphate Biosynthetic Process Nucleoside Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Growth Cell Surface Receptor Signaling Pathway Neuropeptide Signaling Pathway Negative Regulation Of Collecting Lymphatic Vessel Constriction Extracellular Region Diuretic Hormone Activity Protein-containing Complex Striated Muscle Tissue Development Carbohydrate Derivative Metabolic Process Neuropeptide Receptor Binding
Tagcloud ?