NIT1

Description		nitrilase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Deaminated Glutathione Amidase Activity
	Biological Process	Amide Catabolic Process
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: FCER1G
Interacting Genes		3 interacting genes: ATXN1L XRCC6 ZFYVE9
Entrez ID		4817
HPRD ID		07056
Ensembl ID		ENSG00000158793
Uniprot IDs		B7Z410 Q86X76
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Type I Hypersensitivity Mast Cell Apoptotic Process Serotonin Secretion Negative Regulation Of Mast Cell Apoptotic Process IgE Receptor Activity Positive Regulation Of Type IIa Hypersensitivity Serotonin Secretion By Platelet Positive Regulation Of Mast Cell Cytokine Production IgE Binding Regulation Of Mast Cell Apoptotic Process Fc-gamma Receptor III Complex Fc-epsilon Receptor I Complex Positive Regulation Of Type III Hypersensitivity DNA End Binding Cellular Hyperosmotic Salinity Response DNA-dependent Protein Kinase Complex Ku70:Ku80 Complex POZ Domain Binding Positive Regulation Of Hypersensitivity Interleukin-3-mediated Signaling Pathway Hyperosmotic Salinity Response DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Mast Cell Activation Nonhomologous End Joining Complex Nuclear Telomere Cap Complex Double-stranded Telomeric DNA Binding Positive Regulation Of Hematopoietic Stem Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cellular Response To X-ray Cellular Response To Salt Stress Double-strand Break Repair Via Classical Nonhomologous End Joining Neutrophil Activation Involved In Immune Response Serotonin Transport IgG Binding Positive Regulation Of Inflammatory Response To Antigenic Stimulus 1-phosphatidylinositol Binding Plasma Membrane Protein Complex Positive Regulation Of Mast Cell Degranulation Activation Of Immune Response Myeloid Cell Apoptotic Process Regulation Of Acute Inflammatory Response To Antigenic Stimulus Endocytosis Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Defense Response Cellular Hyperosmotic Response Positive Regulation Of Protein Localization To Cell Surface Response To Salt Stress Negative Regulation Of Myeloid Cell Apoptotic Process
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