MTTP

Gene Name		microsomal triglyceride transfer protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Receptor Complex
	Molecular Function	Lipid Transporter Activity Lipid Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Lipoprotein Metabolic Process Small Molecule Metabolic Process
Pathways		Lipoprotein metabolism Metabolism of lipids and lipoproteins Chylomicron-mediated lipid transport Lipid digestion, mobilization, and transport
Drugs		Hesperetin Lomitapide
Diseases
GWAS
Protein-protein Interactions		2 interactors: APOB HSP90B1
Entrez ID		4547
HPRD ID		01144
Ensembl ID		ENSG00000138823
Uniprot IDs		E9PBP6 P55157
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Rod Assembly Receptor-mediated Endocytosis Sequestering Of Calcium Ion Response To Selenium Ion Very-low-density Lipoprotein Particle Assembly Protein Catabolic Process Triglyceride Mobilization Cellular Response To ATP Endocytosis Sequestering Of Metal Ion Low-density Lipoprotein Particle Remodeling Chemical Homeostasis Lipoprotein Catabolic Process Protein-lipid Complex Assembly Positive Regulation Of Cholesterol Storage Cellular Response To Prostaglandin Stimulus Lipoprotein Transport Regulation Of Cholesterol Biosynthetic Process Triglyceride Catabolic Process Low-density Lipoprotein Particle Clearance Acylglycerol Catabolic Process Response To Abiotic Stimulus Response To ATP Plasma Lipoprotein Particle Remodeling Cholesterol Efflux Regulation Of Cholesterol Metabolic Process Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Lipid Storage Regulation Of Phosphoprotein Phosphatase Activity Plasma Lipoprotein Particle Clearance ER-associated Ubiquitin-dependent Protein Catabolic Process Homeostatic Process Protein Transport Regulation Of Macrophage Derived Foam Cell Differentiation Cellular Response To Fatty Acid Vesicle-mediated Transport Establishment Of Protein Localization Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Artery Morphogenesis Sperm Motility Regulation Of Lipid Storage Regulation Of Plasma Lipoprotein Particle Levels Artery Development Sterol Transport Cholesterol Transport Catabolic Process Response To Fatty Acid Regulation Of Steroid Biosynthetic Process Cellular Response To Organic Substance
Tagcloud ?		apob atherosclerosis atherosclerotic causality esters flox foam inference inherited ldlr master mature mll5 mx1 networks pcl pparg regressed regression regulators remnants responding slows sometimes srsf10 tf thp unstable xrn2