MRC1

Gene Name		mannose receptor, C type 1
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Mannose Binding
	Biological Process	Receptor-mediated Endocytosis Signal Transduction Cellular Response To Lipopolysaccharide Cellular Response To Interferon-gamma Cellular Response To Interleukin-4
Pathways		Cross-presentation of soluble exogenous antigens (endosomes) Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation Adaptive Immune System
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21943158) Hematological and biochemical traits ( 20139978)
Protein-protein Interactions		1 interactors: CHEK2
Entrez ID		4360
HPRD ID		01089
Ensembl ID		ENSG00000120586
Uniprot IDs		P22897
PDB IDs		1EGG 1EGI
Enriched GO Terms of Interacting Partners?		Signal Transduction Involved In Intra-S DNA Damage Checkpoint Regulation Of Nuclear Cell Cycle DNA Replication Intra-S DNA Damage Checkpoint DNA Damage Induced Protein Phosphorylation Replicative Senescence Mitotic Spindle Assembly Mitotic Spindle Organization Negative Regulation Of DNA Replication Response To Gamma Radiation Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cell Aging Spindle Assembly Protein Stabilization Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process Mitotic DNA Integrity Checkpoint G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Replication Spindle Organization Regulation Of Protein Stability Response To Ionizing Radiation Double-strand Break Repair DNA Damage Checkpoint Mitotic Cell Cycle Checkpoint Intrinsic Apoptotic Signaling Pathway Protein Autophosphorylation Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Aging Apoptotic Signaling Pathway
Tagcloud ?		accomplished annotated borderline cartilage comp csmd1 discrimination genotyping hampered hip indication influencing knee loci meta oa oligomeric osteoarthritis residuals rs10038 rs1983474 rs691461 scomp snp standardised telopeptide treatoa uctx wide