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LHX8

Description LIM homeobox 8
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
Molecular Function
  • RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA Binding
  • Protein Binding
  • Sequence-specific DNA Binding
  • Metal Ion Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Regulation Of DNA-templated Transcription
  • Regulation Of Transcription By RNA Polymerase II
  • Forebrain Neuron Development
  • Neuron Differentiation
  • Response To Ethanol
Pathways
Drugs
Diseases
GWAS
Interacting Genes 26 interacting genes: - ABI2 ATF2 ATF6B AXIN1 BANP CCHCR1 CRK CSNK2A1 EFS FIGLA FOSL2 FOXN1 GINS4 KLF3 KRT85 LDB2 NEDD9 NUTM1 PLCG2 PRPF31 SCYL3 SUV39H1 TBC1D1 TBC1D22B ZBTB24
Entrez ID 431707
HPRD ID 17275
Ensembl ID ENSG00000162624
Uniprot IDs Q68G74
PDB IDs
Enriched GO Terms of Interacting Partners?
  • NK T Cell Differentiation
  • Nucleus
  • Protein Tyrosine Kinase Binding
  • Response To Endothelin
  • Cellular Response To Endothelin
  • RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
  • Cell Development
  • Signaling Adaptor Activity
  • Response To Yeast
  • Epigenetic Programming In The Zygotic Pronuclei
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Factor Activity
  • Cellular Developmental Process
  • Regulation Of Transcription By RNA Polymerase II
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