MMP7

Gene Name		matrix metallopeptidase 7 (matrilysin, uterine)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding
	Biological Process	Antibacterial Peptide Secretion Antibacterial Peptide Biosynthetic Process Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Regulation Of Cell Proliferation Response To Drug Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Collagen formation Collagen degradation Activation of Matrix Metalloproteinases Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-protein Interactions		16 interactors: BCAN CD151 CD44 DCN FASLG HAPLN1 HBEGF MBP MMP1 MMP9 NGF PLG SERPINA1 SPP1 TFPI TNFSF11
Entrez ID		4316
HPRD ID		01525
Ensembl ID		ENSG00000137673
Uniprot IDs		P09237
PDB IDs		1MMP 1MMQ 1MMR 2DDY 2Y6C 2Y6D
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Leukocyte Migration Cell Migration Cell Motility Wound Healing Response To Wounding Immune System Process Locomotion System Development Response To Stress Movement Of Cell Or Subcellular Component Multicellular Organismal Development Organ Development Regulation Of Endopeptidase Activity Positive Regulation Of Keratinocyte Migration Anatomical Structure Development Regulation Of Peptidase Activity Blood Coagulation Hemostasis Glycosaminoglycan Catabolic Process Response To External Stimulus Response To Organic Substance Pathogenesis Response To Lipid Response To Bacterium Developmental Process Dermatan Sulfate Biosynthetic Process Regulation Of Body Fluid Levels Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process Response To Lipopolysaccharide Positive Regulation Of Bone Resorption Regulation Of Proteolysis Response To Molecule Of Bacterial Origin Tissue Development Response To Other Organism Response To Biotic Stimulus Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Axonogenesis Defense Response Inflammatory Response Response To Stimulus Positive Regulation Of Tissue Remodeling Glycosaminoglycan Metabolic Process Response To Steroid Hormone
Tagcloud ?		a549 a549cis a549cisdkk3 adenocarcinoma betacatenin calu1 calu1cis chemosensitivity cisplatin cisplatinresistant cisplatintreated cmyc dickkopf3 dkk3 ecadherin enhances h460 h460cis h460cisdkk3 inactivated parp proportions reactivation realize rendered retarded sb216763 seeded subline