CHST6

Name	carbohydrate sulfotransferase 6
Structure	No pdb structure
Novel Interactors	1 novel interactors: NUP214
Interactors	None recorded
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Membrane
	Molecular Function	N-acetylglucosamine 6-O-sulfotransferase Activity Sulfotransferase Activity Transferase Activity Keratan Sulfotransferase Activity
	Biological Process	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process Sulfur Compound Metabolic Process Keratan Sulfate Proteoglycan Biosynthetic Process
Pathways	Keratan sulfate biosynthesis Defective CHST6 causes MCDC1
Diseases	Macular corneal dystrophy (MCD); Corneal dystrophy Groenouw type II; Fehr corneal dystrophy
GWAS	Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143 ) Dupuytren's disease ( 28886342 ) Pancreatic cancer ( 25086665 )
Entrez ID	4166
HPRD ID	05597
Ensembl ID	ENSG00000183196
Uniprot IDs	Q9GZX3
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Cytoplasmic Side Of Nuclear Pore Structural Constituent Of Nuclear Pore Nuclear Export Signal Receptor Activity Nuclear Localization Sequence Binding Protein Export From Nucleus RNA Export From Nucleus MRNA Export From Nucleus RNA Transport Protein Import Into Nucleus Import Into Nucleus MRNA Transport Nuclear Export Regulation Of Nucleocytoplasmic Transport Nuclear Pore Protein Localization To Nucleus Nucleobase-containing Compound Transport Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Regulation Of Intracellular Transport Establishment Of Protein Localization To Organelle