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ARHGAP6

Description Rho GTPase activating protein 6
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Cytoskeleton
  • Actin Filament
  • Actin Cytoskeleton
  • Mitotic Spindle
Molecular Function
  • GTPase Activator Activity
  • Phospholipase Activator Activity
  • SH3 Domain Binding
  • Phospholipase Binding
Biological Process
  • Actin Filament Organization
  • Signal Transduction
  • Rho Protein Signal Transduction
  • Actin Filament Polymerization
  • Focal Adhesion Assembly
  • Regulation Of Small GTPase Mediated Signal Transduction
  • Negative Regulation Of Stress Fiber Assembly
  • Negative Regulation Of Focal Adhesion Assembly
  • Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction
  • Positive Regulation Of Intracellular Signal Transduction
Pathways
  • RHOA GTPase cycle
  • RAC3 GTPase cycle
Drugs
Diseases
GWAS
  • Mean spheric corpuscular volume ( 32888494)
  • Prostate cancer ( 29892016)
  • Prostate cancer (advanced) ( 29892016)
Novel Interacting Genes 1 novel interacting genes: TEC
Interacting Genes 2 interacting genes: LNX1 MAP1LC3A
Entrez ID 395
HPRD ID 02124
Ensembl ID ENSG00000047648
Uniprot IDs O43182 Q59HG6
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Phospholipid Binding
  • Response To Iron(II) Ion
  • Response To Oxygen-glucose Deprivation
  • Cellular Response To Oxygen-glucose Deprivation
  • Autolysosome
  • Cellular Response To Nitrogen Starvation
  • Phosphatidylethanolamine Binding
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© Madhavi K. Ganapathiraju 2012-2025