HRNR

Description		hornerin
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Nucleus Cytoplasm Extracellular Matrix Azurophil Granule Lumen Keratohyalin Granule Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Calcium Ion Binding Metal Ion Binding Transition Metal Ion Binding
	Biological Process	Keratinization Cell Envelope Organization Establishment Of Skin Barrier
Pathways		Neutrophil degranulation
Drugs		Zinc Zinc acetate
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Asthma ( 30929738 31619474 31959851) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 30929738 31036433) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Itch intensity from mosquito bite ( 28199695) Male-pattern baldness ( 28196072)
Interacting Genes		5 interacting genes: HSP90AA1 LINC00624 RNF26 UBC USP7
Entrez ID		388697
HPRD ID		17114
Ensembl ID		ENSG00000197915
Uniprot IDs		Q86YZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus CTP Binding DATP Binding Regulation Of Type I Interferon Production Neurofibrillary Tangle Assembly UTP Binding Regulation Of Telomere Maintenance Sulfonylurea Receptor Binding Protein Ubiquitination Protein Modification By Small Protein Conjugation Rho GDP-dissociation Inhibitor Binding Symbiont-mediated Disruption Of Host Cell PML Body Post-translational Protein Modification Chaperone-mediated Autophagy Macromolecule Catabolic Process Sperm Mitochondrial Sheath Nitric-oxide Synthase Regulator Activity Protein Stabilization Regulation Of Intracellular Transport Dendritic Growth Cone Sperm Plasma Membrane TPR Domain Binding Regulation Of Chromosome Organization Telomerase Holoenzyme Complex Assembly Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Perinuclear Region Of Cytoplasm Positive Regulation Of Cardiac Muscle Contraction Inclusion Body Assembly Monoubiquitinated Protein Deubiquitination Ubiquitin Protein Ligase Binding Proteolysis DNA Alkylation Repair Positive Regulation Of Cell Size Protein Unfolding Transcription-coupled Nucleotide-excision Repair Protein Metabolic Process Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Striated Muscle Contraction Striated Muscle Cell Apoptotic Process Regulation Of Telomere Capping Regulation Of Protein Catabolic Process Regulation Of Protein Stability Protein Tag Activity Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Enzyme-substrate Adaptor Activity Negative Regulation Of Defense Response To Virus Endocytic Vesicle Lumen Response To Salt Stress
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